Tracking bio-molecules in live cells using quantum dots

被引：101

作者：

Chang, Yun-Pei ^{[1
]}

Pinaud, Fabien ^{[1
]}

Antelman, Joshua ^{[1
]}

Weiss, Shimon ^{[1
,2
,3
]}

机构：

[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Physiol, Los Angeles, CA 90095 USA

[3] Univ Calif Los Angeles, CNSI, Los Angeles, CA 90095 USA

来源：

JOURNAL OF BIOPHOTONICS | 2008年 / 1卷 / 04期

关键词：

quantum dots; single particle tracking; super-resolution; live cell tracking;

D O I：

10.1002/jbio.200810029

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Single particle tracking (SPT) techniques were developed to explore bio-molecules dynamics in live cells at single molecule sensitivity and nanometer spatial resolution. Recent developments in quantum dots (Qdots) surface coating and bio-conjugation schemes have made them most suitable probes for live cell applications. Here we review recent advancements in using quantum dots as SPT probes for live cell experiments. (C) 2008 by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

引用

页码：287 / 298

页数：12

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