Why rest stimulates bone formation: A hypothesis based on complex adaptive phenomenon

被引：31

作者：

Gross, TS ^{[1
]}

Poliachik, SL ^{[1
]}

Ausk, BJ ^{[1
]}

Sanford, DA ^{[1
]}

Becker, BA ^{[1
]}

Srinivasan, S ^{[1
]}

机构：

[1] Univ Washington, Dept Orthopaed & Sports Med, Orthopaed Sci Labs, Seattle, WA 98107 USA

来源：

EXERCISE AND SPORT SCIENCES REVIEWS | 2004年 / 32卷 / 01期

关键词：

bone; exercise; mechanical loading; mechanotransduction; rest-insertion; small world network;

D O I：

10.1097/00003677-200401000-00003

中图分类号：

Q4 [生理学];

学科分类号：

071003 [生理学];

摘要：

Moderate exercise is an ineffective strategy to build bone mass. The authors present data demonstrating that allowing bone to rest between each load cycle transforms low- and moderate-magnitude mechanical loading into a signal that potently induces bone accretion. They hypothesize that the osteogenic nature of rest-inserted loading arises by enabling osteocytes to communicate as a small world network.

引用

页码：9 / 13

页数：5

共 15 条

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[2]

Buchanan Mark., 2002, NEXUS SMALL WORLDS G

[3]

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