Lack of echocardiographic and Doppler abnormalities in psoriatic arthritis patients without clinically evident cardiovascular disease or classic atherosclerosis risk factors

被引:32
作者
Gonzalez-Juanatey, C
Amigo-Diaz, E
Miranda-Filloy, JA
Testa, A
Revuelta, J
Garcia-Porrua, C
Martin, J
Llorca, J
Gonzalez-Gay, MA
机构
[1] Hosp Xeral Calde, Div Rheumatol, Lugo 27004, Spain
[2] Hosp Xeral Calde, Div Cardiol, Lugo 27004, Spain
[3] Ctr Salud Cospeito, Lugo, Spain
[4] CSIC, Inst Parasitol & Biomed Lopez Neyra, Granada, Spain
[5] Univ Cantabria, Sch Med, E-39005 Santander, Spain
[6] Ctr Salud Cospeito, Lugo, Spain
[7] CSIC, Inst Parasitol & Biomed Lopez Neyra, Granada, Spain
[8] Univ Cantabria, Sch Med, Dept Prevent Med & Publ Hlth, E-39005 Santander, Spain
关键词
psoriatic arthritis; cardiovascular disease; echocardiographic and Doppler findings; classic atherosclerosis risk factors;
D O I
10.1016/j.semarthrit.2005.12.002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE To assess the prevalence of echocardiographic and Doppler abnormalities in psoriatic arthritis (PsA) patients without clinically evident cardiovascular manifestations or classic atherosclerosis risk factors. METHODS Fifty PsA patients were recruited from Hospital Xeral-Calde, Lugo, Spain. Patients seen during the period of recruitment that had classic cardiovascular risk factors or had suffered cardiovascular or cerebrovascular events were excluded. Fifty healthy matched controls were also studied. Echocardiographic and Doppler studies were performed in all cases and controls. RESULTS In PsA patients the frequency of aortic and tricuspid (10%) and mitral regurgitation (16%) was not different from that seen in matched controls (10, 4, and 12%). Also, the pulmonary artery systolic pressure was normal in the group of PsA patients (23.4 +/- 3.9 mm Hg). The prevalence of diastolic dysfunction, in all cases due to impaired relaxation, was similar in PsA patients (28%) and controls (24%) (P = 0.65). In addition, no significant echocardiographic and Doppler differences were observed when PsA patients with polyarticular pattern were compared with the remaining PsA patients. CONCLUSIONS The present study shows that actively treated PsA patients without cardiovascular risk factors or clinically evident cardiovascular disease do not exhibit silent subclinical echocardiographic abnormalities.
引用
收藏
页码:333 / 339
页数:7
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