Reflections on telomeres, growth, aging, and essential hypertension

被引：43

作者：

Aviv, A ^{[1
]}

Aviv, H ^{[1
]}

机构：

[1] UNIV MED & DENT NEW JERSEY, NEW JERSEY MED SCH, CTR HUMAN & MOL GENET, NEWARK, NJ 07103 USA

来源：

HYPERTENSION | 1997年 / 29卷 / 05期

关键词：

telomere; kidney; atherosclerosis; genetics; chromosomes; diabetes mellitus; aging;

D O I：

10.1161/01.HYP.29.5.1067

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Here we review the ''telomere hypothesis of cellular aging.'' We propose that this hypothesis is relevant to our understanding of the roles of genetics as well as growth and development in the etiology of essential hypertension and its cardiovascular complications. Elements of this hypothesis and the speculations that we make can be directly tested using tissues (cells) obtained from human beings.

引用

页码：1067 / 1072

页数：6

共 69 条

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