Long-Term Outcomes in Pediatric Liver Transplantation

被引：42

作者：

Bucuvalas, John ^{[1
]}

机构：

[1] Cincinnati Childrens Hosp, Cincinnati, OH 45229 USA

来源：

LIVER TRANSPLANTATION | 2009年 / 15卷 / 11期

关键词：

FULMINANT HEPATIC-FAILURE; CARDIOVASCULAR RISK-FACTORS; LATE GRAFT LOSS; INTERNATIONAL-SOCIETY; RENAL DYSFUNCTION; HEPATOBLASTOMA; RECIPIENTS; CHILDREN; REJECTION; ADHERENCE;

D O I：

10.1002/lt.21915

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

1. Critical clinical outcomes for pediatric liver transplantation (LT) recipients include (1) patient and graft survival, (2) complications (immune and nonimmune) of chronic immunosuppressive medications, and (3) long-term graft function. 2. Recurrence of malignancy, sepsis, and posttransplant lymphoproliferative disorder account for more than 65% of deaths occurring more than I year after LT. 3. Chronic rejection, late hepatic artery thrombosis, and biliary strictures account for 70% of graft loss occurring more than 1 year after LT. 4. Late histological changes in the allograft are emerging as a common problem in patients more than 5 years after LT. The pathogenesis of these findings and the impact on graft survival remain to be determined. Liver Transpl. 15:S6-S11, 2009. (C) 2009 AASLD.

引用

页码：S6 / S11

页数：6

共 43 条

[1]

Significance of central perivenulitis in pediatric liver transplantation [J].

Abraham, Susan C. ;

Freese, Deborah K. ;

Ishitani, Michael B. ;

Krasinskas, Alyssa M. ;

Wu, Tsung-Teh .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2008, 32 (10) :1479-1488

[2]

Predictive value of the pretreatment extent of disease system in hepatoblastoma: Results from the International Society of Pediatric Oncology Liver Tumor Study Group SIOPEL-1 Study [J].

Aronson, DC ;

Schnater, JM ;

Staalman, CR ;

Weverling, GJ ;

Plaschkes, J ;

Perilongo, G ;

Brown, J ;

Phillips, A ;

Otte, JB ;

Czauderna, P ;

MacKinlay, G ;

Vos, A .

JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (06) :1245-1252

[3]

Calcineurin-inhibitor related nephrotoxicity-reversibility in paediatric liver transplant recipients [J].

Aw, MM ;

Samaroo, B ;

Baker, AJ ;

Verma, A ;

Rela, M ;

Heaton, ND ;

Mieli-Vergani, G ;

Dhawan, A .

TRANSPLANTATION, 2001, 72 (04) :746-749

[4]

Posttransplant survival in pediatric fulminant hepatic failure: the SPLIT experience [J].

Baliga, P ;

Alvarez, S ;

Lindblad, A ;

Zeng, L .

LIVER TRANSPLANTATION, 2004, 10 (11) :1364-1371

[5]

ATHEROSCLEROSIS OF THE AORTA AND CORONARY-ARTERIES AND CARDIOVASCULAR RISK-FACTORS IN PERSONS AGED 6 TO 30 YEARS AND STUDIED AT NECROPSY (THE BOGALUSA HEART-STUDY) [J].

BERENSON, GS ;

WATTIGNEY, WA ;

TRACY, RE ;

NEWMAN, WP ;

SRINIVASAN, SR ;

WEBBER, LS ;

DALFERES, ER ;

STRONG, JP .

AMERICAN JOURNAL OF CARDIOLOGY, 1992, 70 (09) :851-858

[6]

Bucluvalas JC, 2008, CURR OPIN ORGAN TRAN, V13, P247, DOI 10.1097/MOT.0b013e3282f94aab

[7]

Improving Long-Term Outcomes After Liver Transplantation in Children [J].

Bucuvalas, J. C. ;

Alonso, E. ;

Magee, J. C. ;

Talwalkar, J. ;

Hanto, D. ;

Doo, E. .

AMERICAN JOURNAL OF TRANSPLANTATION, 2008, 8 (12) :2506-2513

[8]

High prevalence of renal dysfunction in long-term survivors after pediatric liver transplantation [J].

Campbell, Kathleen M. ;

Yazigi, Nada ;

Ryckman, Frederick C. ;

Alonso, Maria ;

Tiao, Greg ;

Balistreri, William F. ;

Atherton, Harry ;

Bucuvalas, John C. .

JOURNAL OF PEDIATRICS, 2006, 148 (04) :475-480

[9]

Daniel Donna M, 2004, Jt Comm J Qual Saf, V30, P69

[10]

Graft Histology Characteristics in Long-Term Survivors of Pediatric Liver Transplantation [J].

Ekong, Udeme D. ;

Melin-Aldana, Hector ;

Seshadri, Roopa ;

Lokar, Joan ;

Harris, Dave ;

Whitington, Peter F. ;

Alonso, Estella M. .

LIVER TRANSPLANTATION, 2008, 14 (11) :1582-1587

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