Cyclopalladated ferrocenylimines: efficient catalysts for homocoupling and Sonogashira reaction of terminal alkynes

被引：131

作者：

Yang, Fan

Cui, Xiuling

Li, Ya-nan

Zhang, Jinli

Ren, Ge-rui

Wu, Yangjie ^{[1
]}

机构：

[1] Zhengzhou Univ, Dept Chem, Key Lab Chem Biol & Organ Chem Henan Prov, Zhengzhou 450052, Peoples R China

[2] Zhengzhou Univ, Key & Open Lab Appl Chem Henan Univ, Zhengzhou 450052, Peoples R China

来源：

TETRAHEDRON | 2007年 / 63卷 / 09期

基金：

中国国家自然科学基金;

关键词：

cyclopalladated ferrocenylimine; homocoupling; Sonogashira reaction; terminal alkynes;

D O I：

10.1016/j.tet.2006.12.064

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel pathway for homocoupling of terminal alkynes has been described using cyclopalladated ferrocenylimine 1 or 2/CuI as catalyst in the air. This catalytic system could tolerate several functional groups. The palladacycle 2 in the presence of n-Bu4NBR as an additive could be applied to Sonogashira. cross-coupling reaction of aryl iodides, aryl bromides, and some activated aryl chlorides with terminal alkynes under amine- and copper-free conditions, mostly to give moderate to excellent yields. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1963 / 1969

页数：7

共 66 条

[1] Palladium complexes of 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane:: Synthesis, crystal structure and use in the Suzuki and Sonogashira reactions and the α-arylation of ketones [J].