Aquacobalamin (vitamin B12a) does not bind NO in aqueous solution.: Nitrite impurities account for observed reaction

被引：64

作者：

Wolak, M

Stochel, G

Hamza, M

van Eldik, R

机构：

[1] Jagiellonian Univ, Fac Chem, PL-30060 Krakow, Poland

[2] Univ Erlangen Nurnberg, Inst Inorgan Chem, D-91058 Erlangen, Germany

来源：

INORGANIC CHEMISTRY | 2000年 / 39卷 / 10期

关键词：

D O I：

10.1021/ic991266d

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Numerous reports in recent literature claim that NO binds to aquacobalamine (vitamin B-12a) to produce a nitrosyl complex, and that this reaction plays an important role in various biological processes. A careful study of the system has now revealed that there is no reaction between aquacobalamin and NO. The observed reaction is due to the presence of nitrite impurities in aqueous solutions of NO, which react with aquacobalamin to produce the nitrite complex.

引用

页码：2018 / +

页数：3

共 24 条

[1] AUTOXIDATION OF NO IN AQUEOUS-SOLUTION [J].