Limbal epithelial stem cell therapy

被引：24

作者：

Daniels, Julie T.

Notara, Maria

Shortt, Alex J.

Secker, Genevieve

Harris, Anna

Tuft, Stephen J.

机构：

[1] UCL Inst Ophthalmol, Cells Sight Transplantat & Res Programme, Ocular Repair & Regenerat Biol Unit, Div Pathol, London EC1V 9EL, England

[2] Moorfields Eye Hosp NHS Fdn Trust, External Dis Dept, London EC1V 2PD, England

来源：

EXPERT OPINION ON BIOLOGICAL THERAPY | 2007年 / 7卷 / 01期

基金：

英国医学研究理事会;

关键词：

cornea; gene therapy; imaging; limbal epithelial stem cells; regulations; stem cell therapy;

D O I：

10.1517/14712598.7.1.1

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Restoring vision in patients suffering from previously intractable blinding ocular surface disease has become possible with the advent of techniques for ex vivo expansion and transplantation of limbal epithelial stem cells onto the cornea. This approach represents one of the few adult stem cell therapies presently in the clinic. This article highlights several key research areas where progress will be made to specifically understand the biology and therapeutic potential of limbal epithelial stem cells, which may have an applicability to the understanding of other adult stem cell populations.

引用

页码：1 / 3

页数：3

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