Synaptic correlates of odor habituation in the rat anterior piriform cortex

被引:68
作者
Wilson, DA [1 ]
机构
[1] Univ Oklahoma, Dept Zool, Norman, OK 73019 USA
关键词
D O I
10.1152/jn.1998.80.2.998
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Responses of anterior piriform cortex layer II/III neurons to both odors and electrical stimulation of the lateral olfactory tract (LOT) were measured with intracellular recordings in urethan-anesthetized, freely breathing rats. Odor-evoked, respiration-entrained postsynaptic potentials (PSPs) rapidly habituated during a 50-s odor stimulus, then spontaneously recovered within 2 min of odor termination. Associated with the decrease in odor-evoked PSP amplitude was a decrease in the monosynaptic excitatory postsynaptic potentials (EPSPs) evoked by electrical stimulation of the LOT. The decrement in LOT-evoked EPSPs recovered with a time course similar to the odor response recovery. These results demonstrate that odor habituation is associated with a decrease in afferent synaptic efficacy in the anterior piriform cortex.
引用
收藏
页码:998 / 1001
页数:4
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