A biosynthetically significant new bacteriohopanoid present in large amounts in the Caribbean sponge Plakortis simplex

被引：27

作者：

Costantino, V ^{[1
]}

Fattorusso, E ^{[1
]}

Imperatore, C ^{[1
]}

Mangoni, A ^{[1
]}

机构：

[1] Univ Naples Federico II, Dipartimento Chim Sostanze Nat, I-80131 Naples, Italy

来源：

TETRAHEDRON | 2001年 / 57卷 / 18期

关键词：

marine metabolites; terpenes and terpenoids; natural products; polyols;

D O I：

10.1016/S0040-4020(01)00286-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In addition to the previously reported bacteriohopanoids, the marine sponge Plakortis simplex was shown to contain large amounts of (32R,33S,34S)-32,35-anhydrobacteriohopanetetrol The structure of this new bacteriohopanoid was determined by extensive NMR analysis, and further supports the hypothesized biosynthetic pathway to bacteriohopanoids. Altogether, the amounts of bacteriohopanoids in P. simplex is as high as 50% of sterols in weight, and these compounds could play a structural role in the sponge cell membranes. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：4045 / 4048

页数：4

共 7 条

[1] The first 12-methylhopanoid:: 12-methylbacteriohopanetetrol from the marine sponge Plakortis simplex [J].