In-vitro investigation of blood embolization in cancer treatment using magnetorheological fluids

被引:85
作者
Liu, J [1 ]
Flores, GA [1 ]
Sheng, RS [1 ]
机构
[1] Calif State Univ Long Beach, Dept Phys & Astron, Long Beach, CA 90840 USA
基金
美国国家航空航天局;
关键词
magnetorheological fluids; blood vessel seal; cancer therapy; embolization; magnetic seal; iron microspheres; magnetite microspheres;
D O I
10.1016/S0304-8853(00)01260-9
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
In a 'simulated' simple blood network made of silicone tubes, three magnetorheological fluids made of iron and iron-oxide particles are compared for embolizing fluid flow under an applied magnetic field. The sealing strength and seal formation time are measured as a function of particle concentration, magnetic property, carrier fluid, and flow rate. Future applications for cancer therapy are discussed. (C) 2001 Published by Elsevier Science B.V.
引用
收藏
页码:209 / 217
页数:9
相关论文
共 18 条
[1]  
BROWNLEE S, 1998, US NEWS WORLD R 0518, P62
[2]  
CHAKER M, 2000, P 8 INT C EL FLUIDS, P366
[3]  
DALTON WS, 1999, J MOFFITT CANC CTR R, V6, P421
[4]   Magnetic field-induced nonequilibrium structures in a ferrofluid emulsion [J].
Flores, GA ;
Liu, J ;
Mohebi, M ;
Jamasbi, N .
PHYSICAL REVIEW E, 1999, 59 (01) :751-762
[5]  
Flores GA, 2000, P 12 INT C, P716
[6]   Fighting cancer by attacking its blood supply [J].
Folkman, J .
SCIENTIFIC AMERICAN, 1996, 275 (03) :150-+
[7]  
GUPTA S, 1996, MULTIDRUG RESISTANCE
[8]  
Hafeli UO, 1997, SCIENTIFIC AND CLINICAL APPLICATIONS OF MAGNETIC CARRIERS, P501
[9]  
Kuznetsov AA, 1997, SCIENTIFIC AND CLINICAL APPLICATIONS OF MAGNETIC CARRIERS, P379
[10]  
Lubbe AS, 1996, CANCER RES, V56, P4694