New perspectives for the treatment of pulmonary hypertension

被引:46
作者
Baliga, Reshma S. [1 ]
MacAllister, Raymond J. [2 ]
Hobbs, Adrian J. [1 ,2 ]
机构
[1] UCL, Dept Pharmacol, London WC1E 6BT, England
[2] UCL, Dept Clin Pharmacol, London WC1E 6BT, England
基金
英国惠康基金; 英国医学研究理事会;
关键词
pulmonary hypertension; cyclic GMP; guanylate cyclase; phosphodiesterase; endothelin-1; prostacyclin; tyrosine kinase; growth factors; ion channels; SOLUBLE GUANYLATE-CYCLASE; NITRIC-OXIDE SYNTHASE; ENDOTHELIN-RECEPTOR ANTAGONIST; SEROTONIN TRANSPORTER POLYMORPHISMS; VASOACTIVE-INTESTINAL-PEPTIDE; EXPERT CONSENSUS DOCUMENTS; BRAIN NATRIURETIC PEPTIDE; GROWTH-FACTOR EXPRESSION; FOUNDATION TASK-FORCE; RHO-KINASE INHIBITOR;
D O I
10.1111/j.1476-5381.2010.01164.x
中图分类号
R9 [药学];
学科分类号
100702 [药剂学];
摘要
LINKED ARTICLES This article is part of a themed issue on Respiratory Pharmacology. To view the other articles in this issue visit http://dx.doi.org/10.1111/bph.2011.163.issue-1.
引用
收藏
页码:125 / 140
页数:16
相关论文
共 195 条
[1]
Vascular actions of natriuretic peptides - Cyclic GMP-dependent and -independent mechanisms [J].
Ahluwalia, A ;
MacAllister, RJ ;
Hobbs, AJ .
BASIC RESEARCH IN CARDIOLOGY, 2004, 99 (02) :83-89
[2]
Endothelium-derived C-type natriuretic peptide: more than just a hyperpolarizing factor [J].
Ahluwalia, A ;
Hobbs, AJ .
TRENDS IN PHARMACOLOGICAL SCIENCES, 2005, 26 (03) :162-167
[3]
Alexander SPH, 2009, BRIT J PHARMACOL, V158, pS1, DOI 10.1111/j.1476-5381.2009.00499.x
[4]
Role of prostacyclin versus peroxisome proliferator-activated receptor β receptors in prostacyclin sensing by lung fibroblasts [J].
Ali, FY ;
Egan, K ;
FitzGerald, GA ;
Desvergne, B ;
Wahli, W ;
Bishop-Bailey, D ;
Warner, TD ;
Mitchell, JA .
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2006, 34 (02) :242-246
[5]
SHORT-TERM AND LONG-TERM HEMODYNAMIC-EFFECTS OF CAPTOPRIL IN PATIENTS WITH PULMONARY-HYPERTENSION AND SELECTED CONNECTIVE-TISSUE DISEASE [J].
ALPERT, MA ;
PRESSLY, TA ;
MUKERJI, V ;
LAMBERT, CR ;
MUKERJI, B .
CHEST, 1992, 102 (05) :1407-1412
[6]
Phosphodiesterase III inhibitors for heart failure [J].
Amsallem, E ;
Kasparian, C ;
Haddour, G ;
Boissel, JP ;
Nony, P .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2005, (01)
[7]
Nitric oxide deficiency in fenfluramine- and dexfenfluramine-induced pulmonary hypertension [J].
Archer, SL ;
Djaballah, K ;
Humbert, M ;
Weir, EK ;
Fartoukh, M ;
DalL'Ava-Santucci, J ;
Mercier, JC ;
Simonneau, G ;
Dinh-Xuan, AT .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1998, 158 (04) :1061-1067
[8]
Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor [J].
Atkinson, C ;
Stewart, S ;
Upton, PD ;
Machado, R ;
Thomson, JR ;
Trembath, RC ;
Morrell, NW .
CIRCULATION, 2002, 105 (14) :1672-1678
[9]
Longterm Survival Among Patients with Scleroderma-associated Pulmonary Arterial Hypertension Treated with Intravenous Epoprostenol [J].
Badesch, David B. ;
McGoon, Michael D. ;
Barst, Robin J. ;
Tapson, Victor F. ;
Rubin, Lewis J. ;
Wigley, Fredrick M. ;
Kral, Kenneth M. ;
Raphiou, Ibrahim H. ;
Crater, Glenn D. .
JOURNAL OF RHEUMATOLOGY, 2009, 36 (10) :2244-2249
[10]
Synergy between natriuretic peptides and phosphodiesterase 5 inhibitors ameliorates pulmonary arterial hypertension [J].
Baliga, Reshma S. ;
Zhao, Lan ;
Madhani, Melanie ;
Lopez-Torondel, Belen ;
Visintin, Cristina ;
Selwood, David ;
Wilkins, Martin R. ;
MacAllister, Raymond J. ;
Hobbs, Adrian J. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2008, 178 (08) :861-869