Osteoarthritis

被引：145

作者：

Haq, I

Murphy, E

Dacre, J

机构：

[1] UCL, Acad Ctr Med Educ, London N19 3LW, England

[2] Whittington Hosp NHS Trust, Dept Rheumatol, London, England

来源：

POSTGRADUATE MEDICAL JOURNAL | 2003年 / 79卷 / 933期

关键词：

D O I：

10.1136/pmj.79.933.377

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Osteoarthritis is a chronic degenerative disorder characterised by cartilage loss. It is extremely prevalent in society and is a major cause of disability. It is important to treat osteoarthritis effectively using a multidisciplinary approach tailored to the patient's needs. This paper reviews current thinking on the aetiology, pathogenesis, investigations, and management of osteoarthritis. The paper also discusses the challenges for developing good quality outcome measures for use in large scale multicentre clinical trials for new osteoarthritis treatments, especially disease modifying osteoarthritis drugs.

引用

页码：377 / 383

页数：7

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