Peripheral nerve regeneration along collagen filaments

被引：65

作者：

Yoshii, S

Oka, M

机构：

[1] Kansai Denryoku Hosp, Inst Biomed Engn, Asahi Ku, Osaka 5350011, Japan

[2] Kyoto Univ, Inst Frontier Med Sci, Dept Tissue Regenerat, Kyoto, Japan

来源：

BRAIN RESEARCH | 2001年 / 888卷 / 01期

关键词：

nerve; peripheral; regeneration; axon; collagen; filament;

D O I：

10.1016/S0006-8993(00)03025-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

This paper describes the regeneration of severed peripheral nerve axons along collagen filaments without a tube. Two thousand collagen filaments were grafted to bridge 20 mm defects of rat sciatic nerve. The number of myelinated axons was approximately 4800 in the distal end of the nerve autograft at 8 weeks postoperatively; while in the collagen-filaments nerve guide it was 5500. The results suggested the collagen filaments guided regenerating axons effectively. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：158 / 162

页数：5

共 27 条

[1] Peripheral nerve regeneration through nerve guides seeded with adult Schwann cells [J].