Biomagnification of cycad neurotoxins in flying foxes - Implications for ALS-PDC in Guam

被引：200

作者：

Banack, SA

Cox, PA

机构：

[1] Natl Trop Bot Garden, Inst Ethnobot, Kauai, HI 96741 USA

[2] Calif State Univ Fullerton, Dept Biol Sci, Fullerton, CA 92634 USA

来源：

NEUROLOGY | 2003年 / 61卷 / 03期

关键词：

D O I：

10.1212/01.WNL.0000078320.18564.9F

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

beta-Methylamino-L-alanine (BMAA) occurs in higher levels in museum specimens of the Guamanian flying fox than in the cycad seeds the flying foxes feed on, confirming the hypothesis that cycad neurotoxins are biomagnified within the Guam ecosystem. Consumption of a single flying fox may have resulted in an equivalent BMAA dose obtained from eating 174 to 1,014 kg of processed cycad flour. Traditional feasting on flying foxes may be related to the prevalence of neuropathologic disease in Guam.

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页码：387 / 389

页数：3

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