Diagnosis and assessment of pain associated with herpes zoster and postherpetic neuralgia

被引:168
作者
Dworkin, Robert H. [1 ,2 ]
Gnann, John W., Jr. [3 ,4 ]
Oaklander, Anne Louise [5 ]
Raja, Srinivasa N. [6 ]
Schmader, Kenneth E. [7 ]
Whitley, Richard J. [8 ]
机构
[1] Univ Rochester, Sch Med & Dent, Dept Anesthesiol, Rochester, NY 14642 USA
[2] Univ Rochester, Sch Med & Dent, Dept Neurol, Rochester, NY 14642 USA
[3] Univ Alabama Birmingham, Dept Med, Birmingham, AL 35294 USA
[4] Birmingham VA Med Ctr, Birmingham, AL 35294 USA
[5] Harvard Univ, Dept Neurol, Boston, MA 02115 USA
[6] Johns Hopkins Univ, Sch Med, Dept Anesthesiol & Crit Care Med, Baltimore, MD 21205 USA
[7] Duke Univ, Durham VA Med Ctr, Dept Med, Durham, NC USA
[8] Univ Alabama Birmingham, Dept Pediat, Birmingham, AL USA
关键词
herpes zoster; postherpetic neuralgia; diagnosis; assessment; acute pain; chronic pain;
D O I
10.1016/j.jpain.2007.10.008
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Accurate evaluation of pain plays a critical role in identifying new interventions for the treatment and prevention of herpes zoster and postherpetic neuralgia (PHN). Different types of pain and other sensory symptoms are found in patients with herpes zoster, and these vary greatly with respect to their presence, location, duration, intensity, and quality. The results of recent studies of herpes zoster and PHN and the development of new methods for assessing neuropathic pain provide a foundation for diagnosing and assessing the pain associated with herpes zoster. We review the results of recent research to identify the essential components that must be considered in developing an evidence-based description of pain associated with herpes zoster and PHN. Perspective: Comprehensive assessments of pain are necessary for clinical research on the epidemiology, natural history, pathophysiologic mechanisms, treatment and prevention of pain in herpes zoster and PHN. (c) 2008 by the American Pain Society.
引用
收藏
页码:S37 / S44
页数:8
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