Impact of Nanotechnology on Drug Delivery

被引：2494

作者：

Farokhzad, Omid C. ^{[1
,2
,3
,4
]}

Langer, Robert ^{[4
,5
]}

机构：

[1] Brigham & Womens Hosp, Lab Nanomed & Biomat, Boston, MA 02115 USA

[2] Brigham & Womens Hosp, Dept Anesthesiol, Boston, MA 02115 USA

[3] Harvard Univ, Sch Med, Boston, MA 02115 USA

[4] MIT, Harvard Ctr Canc Nanotechnol Excellence, Cambridge, MA 02139 USA

[5] MIT, Dept Chem Engn, Cambridge, MA 02139 USA

来源：

ACS NANO | 2009年 / 3卷 / 01期

关键词：

CANCER-CHEMOTHERAPY; TUMOR-LOCALIZATION; NANOPARTICLES; LIPOSOMES; ANTIBODY; INTERNALIZATION; ACCUMULATION; PENETRATION; PROTEINS; MEDICINE;

D O I：

10.1021/nn900002m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nanotechnology is the engineering and manufacturing of materials at the atomic and molecular scale. in its strictest definition from the National Nanotechnology Initiative, nanotechnology refers to structures roughly in the 1-100 nm size regime in at least one dimension. Despite this size restriction, nanotechnology commonly refers to structures that are up to several hundred nanometers in size and that are developed by top-down or bottom-up engineering of individual components. Herein, we focus on the application of nanotechnology to drug delivery and highlight several areas of opportunity where current and emerging nanotechnologies could enable entirely novel classes of therapeutics.

引用

页码：16 / 20

页数：5

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