HLA-DQ1 associated with reflex sympathetic dystrophy

被引:75
作者
Kemler, MA
van de Vusse, AC
van den Berg-Loonen, EM
Barendse, GAM
van Kleef, M
Weber, WEJ
机构
[1] Maastricht Univ Hosp, Dept Anesthesiol, Pain Management & Res Ctr, NL-6202 AZ Maastricht, Netherlands
[2] Maastricht Univ Hosp, Dept Surg, NL-6202 AZ Maastricht, Netherlands
[3] Maastricht Univ Hosp, Tissue Typing Lab, NL-6202 AZ Maastricht, Netherlands
关键词
HLA-DQ1; reflex sympathetic dystropy;
D O I
10.1212/WNL.53.6.1350
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Reflex sympathetic dystrophy (RSD) is a relatively common disabling disorder of unknown pathophysiology. From a cohort of 52 patients, carefully selected to fulfill the recently formulated diagnostic criteria for RSD, venous blood samples were taken for typing of class I and II major histocompatibility antigens. The frequency of HLA-DQ1 was found to be significantly increased compared with control frequencies. The association provides an indication for an organic basis of RSD.
引用
收藏
页码:1350 / 1351
页数:2
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