From secondary prevention to primary prevention: a unique strategy that gives hope to a country ravaged by meningococcal disease

被引:41
作者
O'Hallahan, J
Lennon, D
Oster, P
Lane, R
Reid, S
Mulholland, K
Stewart, J
Penney, L
Percival, T
Martin, D
机构
[1] Minist Hlth, Wellington, New Zealand
[2] Univ Auckland, Auckland 1, New Zealand
[3] Chiron Vaccines, Siena, Italy
[4] Ropata Med Ctr, Lower Hutt, New Zealand
[5] Univ Melbourne, Ctr Int Child Hlth, Melbourne, Vic, Australia
[6] Massey Univ, SHORE Ctr, Te Ropu Whariki, Auckland, New Zealand
[7] KidzFirst Childrens Hosp, Auckland, New Zealand
[8] Inst Environm Sci & Res, Porirua, New Zealand
关键词
meningococcal disease; immunisation programme; epidemic control;
D O I
10.1016/j.vaccine.2005.01.061
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
New Zealand has been affected by an epidemic of group B meningococcal disease dominated by a strain defined as, B:4:P1.7b,4. Over 5550 cases and 222 deaths have been reported since 1991 in a population of 4 million people. (1) Through the collaborative efforts of a government agency, vaccine company, university and laboratory institute, clinical trials of the Chiron produced outer membrane vesicle (OMV) strain-specific MeNZB (TM) vaccine were run in rapid succession. The delivery of MeNZB (TM) Will be New Zealand's largest immunisation programme with three doses given at 6-week intervals to over 1 million people aged 6 weeks-19 year olds inclusive. Planning, co-ordinating and delivering the immunisation programme is a challenging project for the New Zealand Health Sector. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2197 / 2201
页数:5
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