Microwave-assisted solid-phase peptide synthesis utilizing N-Fmoc-Protected (α-aminoacyl)benzotriazoles

被引：19

作者：

Katritzky, Alan R. ^{[1
]}

Khashab, Niveen M.

Yoshioka, Megumi

Haase, Danniebelle N.

Wilson, Krista R.

Johnson, Jodie V.

Chung, Alfred

Haskell-Luevano, Carrie

机构：

[1] Univ Florida, Ctr Heterocycl Cpds, Dept Chem, Gainesville, FL 32611 USA

[2] Univ Florida, Dept Med Chem, Gainesville, FL 32610 USA

[3] Univ Florida, Dept Chem, Gainesville, FL 32611 USA

[4] Univ Florida, Interdisciplary Ctr Biotechnol Res, PROTEOMICS, Gainesville, FL 32611 USA

来源：

CHEMICAL BIOLOGY & DRUG DESIGN | 2007年 / 70卷 / 05期

关键词：

microwave irradiation; N-Fmoc-protected(alpha-aminoacyl) benzotriazole; peptides; Rink amide resin; solid-phase peptide synthesis;

D O I：

10.1111/j.1747-0285.2007.00584.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel microwave-assisted solid-phase peptide synthesis utilizing N-Fmoc-protected(alpha-aminoacyl)benzotriazoles was applied in the preparation of tri-, tetra-, penta-, hexa-, and heptapeptides in 71% average crude yield.

引用

页码：465 / 468

页数：4

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