Fate and function of lymphoid tissue inducer cells

被引：39

作者：

Finke, D ^{[1
]}

机构：

[1] Univ Basel, Ctr Biomed Dev Immunol, Dept Klin Biol Wissenschaften, CH-4058 Basel, Switzerland

来源：

CURRENT OPINION IN IMMUNOLOGY | 2005年 / 17卷 / 02期

关键词：

D O I：

10.1016/j.coi.2005.01.006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The discovery that Peyer's patch and lymph node development is regulated by the collaboration between fetal hematopoietic cells and mesenchymal cells has thrown new light on our understanding of the mechanisms underlying the formation of lymphoid organs. Lymphoid tissue inducer cells trigger a coordinated series of events leading to cell clustering and changes in gene expression and differentiation. Nevertheless, many questions regarding the origin, recruitment and fate of the inducer cells and cellular crosstalk with neighboring cells remain unanswered.

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页码：144 / 150

页数：7

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