Combined schedule of 7-valent pneumococcal conjugate vaccine followed by 23-valent pneumococcal vaccine in children and young adults with sickle cell disease

被引：77

作者：

Vernacchio, L

Neufeld, EJ

MacDonald, K

Kurth, S

Murakami, S

Hohne, C

King, M

Molrine, D

机构：

[1] Dana Farber Canc Inst, Infect Dis Lab, Boston, MA 02115 USA

[2] Boston Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Boston, MA USA

[3] Childrens Hosp, Div Hematol Oncol, Boston, MA 02115 USA

来源：

JOURNAL OF PEDIATRICS | 1998年 / 133卷 / 02期

关键词：

D O I：

10.1016/S0022-3476(98)70235-5

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We compared the immunogenicity of 7-valent pneumococcal-conjugate vaccine plus 23-valent pneumococcal vaccine to immunization with 23-valent vaccine only in individuals greater than or equal to 2 years of age with sickle cell disease. IgG pneumococcal antibody concentrations were higher in the combined schedule group with no increase in side effects observed after immunization with 23-valent vaccine.

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页码：275 / 278

页数：4

相关论文

共 12 条

[1] Immunogenicity of heptavalent pneumococcal conjugate vaccine in infants [J].

Anderson, EL ;

Kennedy, DJ ;

Geldmacher, KM ;

Donnelly, J ;

Mendelman, PM .

JOURNAL OF PEDIATRICS, 1996, 128 (05) :649-653

[2]

CHAN CY, 1996, J INFECT DIS, V173, P266

[3] CLINICAL EVENTS IN THE FIRST DECADE IN A COHORT OF INFANTS WITH SICKLE-CELL DISEASE [J].

GILL, FM ;

SLEEPER, LA ;

WEINER, SJ ;

BROWN, AK ;

BELLEVUE, R ;

GROVER, R ;

PEGELOW, CH ;

VICHINSKY, E .

BLOOD, 1995, 86 (02) :776-783

[4] PNEUMOCOCCAL VACCINE IN NORMAL-CHILDREN [J].

LAWRENCE, EM ;

EDWARDS, KM ;

SCHIFFMAN, G ;

THOMPSON, JM ;

VAUGHN, WK ;

WRIGHT, PF .

AMERICAN JOURNAL OF DISEASES OF CHILDREN, 1983, 137 (09) :846-850

[5] ANTIBODY-RESPONSE TO 14-VALENT PNEUMOCOCCAL CAPSULAR POLYSACCHARIDE VACCINE IN PRESCHOOL AGE CHILDREN [J].

LEINONEN, M ;

SAKKINEN, A ;

KALLIOKOSKI, R ;

LUOTONEN, J ;

TIMONEN, M ;

MAKELA, PH .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1986, 5 (01) :39-44

[6] IMPAIRED HUMAN RESPONSES TO TETANUS TOXOID IN VITAMIN-A-DEFICIENT SCID MICE RECONSTITUTED WITH HUMAN PERIPHERAL-BLOOD LYMPHOCYTES [J].

MOLRINE, DC ;

POLK, DB ;

CIAMARRA, A ;

PHILLIPS, N ;

AMBROSINO, DM .

INFECTION AND IMMUNITY, 1995, 63 (08) :2867-2872

[7] Pneumococcal colonization in children with sickle cell disease [J].

Norris, CF ;

Mahannah, SR ;

SmithWhitley, K ;

OheneFrempong, K ;

McGowan, KL .

JOURNAL OF PEDIATRICS, 1996, 129 (06) :821-827

[8] A glycoprotein pneumococcal conjugate vaccine primes for antibody responses to a pneumococcal polysaccharide vaccine in Gambian children [J].

Obaro, SK ;

Huo, ZM ;

Banya, WAS ;

Henderson, MC ;

Monteil, MA ;

Leach, A ;

Greenwood, BM .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1997, 16 (12) :1135-1140

[9] Immunologic priming of young children by pneumococcal glycoprotein conjugate, but not polysaccharide, vaccines [J].

OBrien, KL ;

Steinhoff, MC ;

Edwards, K ;

Keyserling, H ;

Thoms, ML ;

Madore, D .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1996, 15 (05) :425-430

[10] ASSIGNMENT OF WEIGHT-BASED ANTIBODY UNITS TO A HUMAN ANTIPNEUMOCOCCAL STANDARD REFERENCE SERUM, LOT 89-S [J].

QUATAERT, SA ;

KIRCH, CS ;

WIEDL, LJQ ;

PHIPPS, DC ;

STROHMEYER, S ;

CIMINO, CO ;

SKUSE, J ;

MADORE, DV .

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 1995, 2 (05) :590-597