Immunohistochemical localization of the angiotensin II type 1 receptor in human hypothalamus and brainstem

被引：15

作者：

Benarroch, EE ^{[1
]}

Schmeichel, AM ^{[1
]}

机构：

[1] Mayo Clin, Dept Neurol, Rochester, MN 55905 USA

来源：

BRAIN RESEARCH | 1998年 / 812卷 / 1-2期

关键词：

AT-1; receptor; autonomic; endocrine; olivocerebellar system;

D O I：

10.1016/S0006-8993(98)00982-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We studied the distribution of the angiotensin II type 1 (AT-1) receptor using a polyclonal rabbit antibody in two human brains. AT-1 receptor immunoreactivity was detected in several hypothalamic nuclei, substantia nigra, locus coeruleus, nucleus tractus solitarius, ventrolateral medulla, pontine nuclei, and inferior olivary nucleus. This provides direct evidence of neuronal localization of the AT-1 receptor in autonomic and motor areas in human brain. (C) 1998 Elsevier Science B.V. All rights reserved.

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收藏

页码：292 / 296

页数：5

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