Assisted reproductive technology in Europe, 2007: results generated from European registers by ESHRE

This 11th European IVF-monitoring report presents the results of assisted reproductive technology (ART) treatments initiated in Europe during 2007. From 33 countries, 1029 clinics reported 493 184 treatment cycles: IVF (120 761), ICSI (256 642), frozen embryo replacement (91 145), egg donation (15 731), preimplantation genetic diagnosis/preimplantation genetic screening (4638), in vitro maturation (660) and frozen oocytes replacements (3607). Overall, this represents a 7.6 increase since 2006, mostly related to an increase in all registers. IUI using husband/partners (IUI-H) and donor (IUI-D) semen was reported from 23 countries: 142 609 IUI-H (6.2) and 26 088 IUI-D (7.2). In 18 countries where all clinics reported, 376 971 ART cycles were performed in a population of 425.6million (886 cycles per million). The clinical pregnancy rates per aspiration and per transfer were 29.1 and 32.8 for IVF, and 28.6 and 33.0 for ICSI. Delivery rate after IUI-H was 10.2 in women aged 40 years. In IVF/ICSI cycles, 1, 2, 3 and epsilon 4 embryos were transferred in 21.4, 53.4, 22.7 and 2.5 of cycles, with no decline in the number of embryos per transfer since 2006. The proportion of multiple deliveries (22.3: 21.3 twin and 1.0 triplet), did not decrease compared with 2006 (20.8) and 2005 (21.8). In women 40 years undergoing IUI-H, twin deliveries occurred in 11.7 and triplets in 0.5. In comparison with previous years, the reported number of ART cycles in Europe increased in 2007; pregnancy rates increased marginally, but the earlier decline in the number of embryos transferred and multiple births did not continue.