Rac and cell migration: CDM proteins integrate signals

被引：7

作者：

Bourne, HR ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Mol & Cellular Pharmacol, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA

[3] Univ Calif San Francisco, Cardiovasc Res Inst, San Francisco, CA 94143 USA

来源：

NATURE CELL BIOLOGY | 2005年 / 7卷 / 08期

关键词：

D O I：

10.1038/ncb0805-777

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cell migration requires that Rac GTPases promote formation of actin polymers at the cell's leading edge. An activator of Rac, DOCK180, accomplishes this localization by using its DHR-1 domain to bind phosphatidylinositol-3,4,5-trisphosphate at the membrane.

引用

页码：777 / 778

页数：2

共 14 条

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