Micronutrient needs of malnourished children

被引:49
作者
Bhutta, Zulfiqar A. [1 ]
机构
[1] Aga Khan Univ, Dept Paediat & Child Hlth, Karachi 74800, Pakistan
关键词
fortification; multiple micronutrients; supplementation; vitamin A; zinc;
D O I
10.1097/MCO.0b013e3282fbf5a0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review In addition to overt manifestations of undernutrition such as stunting, wasting and underweight, micronutrient deficiencies are also recognized as important components of the spectrum of malnutrition. This review focuses on recent advances in our understanding of undernutrition and micronutrient deficiencies during childhood from a review of the literature over the last 18 months (August 2006-January 2008). Recent findings There is considerable advance in our understanding of the epidemiology and burden of childhood undernutrition and micronutrient deficiencies. Based on recent surveys, an estimated 32% (178 million) of children under 5 years of age were stunted. The corresponding global estimate of wasting is 10% (55 million children), of which 3.5% (119 million children) are severely wasted. It is estimated that nearly 11% of all children under 5 years of age, die due to four micronutrient deficiencies (vitamin A, zinc, iron and iodine). There is evidence from recent reviews of evidence-based interventions that administering single or multiple micronutrients can make a significant difference to health outcomes. However, delivery strategies may differ and recent data suggest that fortification may be a more efficient strategy to deliver multiple micronutrients. Summary These findings support the scaling up of evidence-based interventions to prevent and treat such deficiencies and to integrate these within health systems.
引用
收藏
页码:309 / 314
页数:6
相关论文
共 41 条
[1]   Longitudinal assessment of micronutrient intake among African-American and white girls: The National Heart, Lung, and Blood Institute Growth and Health Study [J].
Affenito, Sandra G. ;
Thompson, Douglas R. ;
Franko, Debra L. ;
Striegel-Moore, Ruth H. ;
Daniels, Stephen R. ;
Barton, Bruce A. ;
Schreiber, George B. ;
Schmidt, Marcia ;
Crawford, Patricia B. .
JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION, 2007, 107 (07) :1113-1123
[2]   Role of zinc administration in prevention of childhood diarrhea and respiratory illnesses: A meta-analysis [J].
Aggarwal, Rakesh ;
Sentz, John ;
Miller, Mark A. .
PEDIATRICS, 2007, 119 (06) :1120-1130
[3]  
Bhandari N, 2007, J NUTR, V137, P112
[4]   Maternal and Child Undernutrition 3 - What works? Interventions for maternal and child undernutrition and survival [J].
Bhutta, Zulfiqar A. ;
Ahmed, Tahmeed ;
Black, Robert E. ;
Cousens, Simon ;
Dewey, Kathryn ;
Giugliani, Elsa ;
Haider, Botool A. ;
Kirkwood, Betty ;
Morris, Saul S. ;
Sachdev, H. P. S. ;
Shekar, Meera .
LANCET, 2008, 371 (9610) :417-440
[5]   Effect of infections and environmental factors on growth and nutritional status in developing countries [J].
Bhutta, Zulfiqar Ahmed .
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2006, 43 :S13-S21
[6]   Maternal and child undernutrition 1 - Maternal and child undernutrition: global and regional exposures and health consequences [J].
Black, Robert E. ;
Allen, Lindsay H. ;
Bhutta, Zulfiqar A. ;
Caulfield, Laura E. ;
de Onis, Mercedes ;
Ezzati, Majid ;
Mathers, Colin ;
Rivera, Juan .
LANCET, 2008, 371 (9608) :243-260
[7]   Effect of supplemental zinc on the growth and serum zinc concentrations of prepubertal children: a meta-analysis of randomized controlled trials [J].
Brown, KH ;
Peerson, JM ;
Rivera, J ;
Allen, LH .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2002, 75 (06) :1062-1071
[8]   Countdown to 2015: tracking intervention coverage for child survival [J].
Bryce, Jennifer ;
Terreri, Nancy ;
Victora, Cesar G. ;
Mason, Elizabeth ;
Daelmans, Bernadette ;
Bhutta, Zulfiqar A. ;
Bustreo, Flavia ;
Songane, Francisco ;
Salama, Peter ;
Wardlaw, Tessa .
LANCET, 2006, 368 (9541) :1067-1076
[9]  
Chen KJ, 2007, ASIA PAC J CLIN NUTR, V16, P572
[10]   Asymptomatic rickets in adolescent girls [J].
Dahifar, Hossein ;
Faraji, Ali ;
Yassobi, Saeid ;
Ghorbani, Aboulfazl .
INDIAN JOURNAL OF PEDIATRICS, 2007, 74 (06) :571-575