Iridium-catalyzed reduction of alkyl halides by triethylsilane

被引：108

作者：

Yang, Jian ^{[1
]}

Brookhart, Maurice ^{[1
]}

机构：

[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 42期

关键词：

D O I：

10.1021/ja075725i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly active cationic Ir(III) hydride complex catalyzes the reduction of primary, secondary, and tertiary chlorides, bromides, and iodides as well as certain fluorides by Et3SiH. The catalytic cycle appears to operate by a unique process in which an electrophilic iridium silane complex acts as a silylating reagent to produce a silyl-substituted halonium ion which is then readily reduced by the nucleophilic dihydride formed following silyl transfer.

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页码：12656 / +

页数：3

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