Oxidative intramolecular phenolic coupling reaction induced by a hypervalent iodine(III) reagent: Leading to galanthamine-type amaryllidaceae alkaloids

被引：157

作者：

Kita, Y ^{[1
]}

Arisawa, M ^{[1
]}

Gyoten, M ^{[1
]}

Nakajima, M ^{[1
]}

Hamada, R ^{[1
]}

Tohma, H ^{[1
]}

Takada, T ^{[1
]}

机构：

[1] Osaka Univ, Grad Sch Pharmaceut Sci, Osaka 5650871, Japan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1998年 / 63卷 / 19期

关键词：

D O I：

10.1021/jo9807868

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

By extending our oxidative phenol-coupling reactions using a hypervalent iodine(III) reagent, a versatile synthetic procedure for the galanthamine-type Amaryllidaceae alkaloids was accomplished. The first total synthesis of (+/-)-sanguinine and the total syntheses of (+/-)-galanthamine, (+/-)-narwedine, (+/-)-lycoramine, and (+/-)-norgalanthamine were also successfully carried out.

引用

页码：6625 / 6633

页数：9

共 107 条

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