Dexmedetomidine as the primary sedative agent for brain radiation therapy in a 21-month old child

被引:27
作者
Shukry, M [1 ]
Ramadhyani, U [1 ]
机构
[1] Tulane Univ, Dept Anesthesiol, New Orleans, LA 70118 USA
关键词
sedation; radiation therapy; dexmedetomidine;
D O I
10.1111/j.1460-9592.2005.01418.x
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Dexmedetomidine (Precedex(TM)) is an alpha(2) adrenoceptor agonist which is gaining popularity as a sedative and anesthetic adjuvant. In this case report, dexmedetomidine was used safely and easily to provide sedation for 12 radiation-therapy sessions in a pediatric patient. It provided smooth induction and fast recovery with minimal respiratory depression.
引用
收藏
页码:241 / 242
页数:2
相关论文
共 4 条
[1]   EFFECTS OF INTRAVENOUS DEXMEDETOMIDINE IN HUMANS .1. SEDATION, VENTILATION, AND METABOLIC-RATE [J].
BELLEVILLE, JP ;
WARD, DS ;
BLOOR, BC ;
MAZE, M .
ANESTHESIOLOGY, 1992, 77 (06) :1125-1133
[2]   Anesthesia for pediatric external beam radiation therapy [J].
Fortney, JT ;
Halperin, EC ;
Hertz, CM ;
Schulman, SR .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1999, 44 (03) :587-591
[3]   Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. 1: Pharmacodynamic and pharmacokinetic interactions [J].
Khan, ZP ;
Munday, IT ;
Jones, RM ;
Thornton, C ;
Mant, TG ;
Amin, D .
BRITISH JOURNAL OF ANAESTHESIA, 1999, 83 (03) :372-380
[4]   DEXMEDETOMIDINE DECREASES SEIZURE THRESHOLD IN A RAT MODEL OF EXPERIMENTAL GENERALIZED EPILEPSY [J].
MIRSKI, MAZ ;
ROSSELL, LA ;
MCPHERSON, RW ;
TRAYSTMAN, RJ .
ANESTHESIOLOGY, 1994, 81 (06) :1422-1428