Cellular fatty acid profile distinguishes Burkholdefia pseudomallei from avirulent Burkholdefia thadandensis

被引：25

作者：

Inglis, TJJ ^{[1
]}

Aravena-Roman, M

Ching, S

Croft, K

Wuthiekamm, V

Mee, BJ

机构：

[1] Univ Western Australia, Sch Biomed & Chem Sci, Western Australian Ctr Pathol & Med Res, Div Microbiol & Infect Dis, Nedlands, WA 6909, Australia

[2] Univ Western Australia, Sch Biomed & Chem Sci, Div Clin Pathol, Western Australian Ctr Pathol & Med Res, Nedlands, WA 6909, Australia

[3] Univ Western Australia, Sch Biomed & Chem Sci, Div Microbiol, Nedlands, WA 6909, Australia

[4] Univ Western Australia, Dept Med, Perth, WA 6009, Australia

[5] Mahidol Univ, Wellcome Trop Dis Res Unit, Bangkok 10700, Thailand

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2003年 / 41卷 / 10期

关键词：

D O I：

10.1128/JCM.41.10.4812-4814.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Burkholderia pseudomallei, the cause of melioidosis, can be distinguished from the closely related but nonpathogenic Burkholderia thailandensis by gas chromatography (GC) analysis of fatty acid derivatives. A 2-hydroxymyristic acid derivative (14:0 20H) was present in 95% of B. pseudomallei isolates and no B. thailandensis isolates. GC mass spectrophotometry confirmed that 2-hydroxymyristic acid was present in B. pseudomallei. GC-fatty acid methyl ester analysis may be useful in distinguishing these two closely related species.

引用

页码：4812 / 4814

页数：3

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