Proton magnetic resonance spectroscopy and morphometry of the hippocampus in chronic fatigue syndrome

被引:44
作者
Brooks, JCW
Roberts, N
Whitehouse, G
Majeed, T
机构
[1] Univ Liverpool, Magnet Resonance & Image Anal Res Ctr, Liverpool L69 3BX, Merseyside, England
[2] Ctr Clin Sci, Pain Relief Fdn, Liverpool, Merseyside L9 7AL, England
[3] Royal Preston Hosp, Dept Neurol, Preston, Lancs PR2 9HT, England
关键词
D O I
10.1259/bjr.73.875.11144799
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Seven patients with chronic fatigue syndrome (CFS) were matched with ten healthy control subjects of similar age. Hippocampal volume, obtained from magnetic resonance images using an unbiased method, showed no difference between the two groups, whereas proton magnetic resonance spectroscopy showed a significantly reduced concentration of N-acetylaspartate in the right hippocampus of CFS patients (p=0.005).
引用
收藏
页码:1206 / 1208
页数:3
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