Serial SimCoal: A population genetics model for data from multiple populations and points in time

被引：167

作者：

Anderson, CNK ^{[1
]}

Ramakrishnan, U ^{[1
]}

Chan, YL ^{[1
]}

Hadly, EA ^{[1
]}

机构：

[1] Stanford Univ, Dept Biol Sci, Stanford, CA 94305 USA

来源：

BIOINFORMATICS | 2005年 / 21卷 / 08期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1093/bioinformatics/bti154

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We present Serial SimCoal, a program that models population genetic data from multiple time points, as with ancient DNA data. An extension of SIMCOAL, it also allows simultaneous modeling of complex demographic histories, and migration between multiple populations. Further, we incorporate a statistical package to calculate relevant summary statistics, which, for the first time allows users to investigate the statistical power provided by, conduct hypothesis-testing with, and explore sample size limitations of ancient DNA data.

引用

页码：1733 / 1734

页数：2

共 9 条

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