High prevalence of viral genomes and inflammation in peripartum cardiomyopathy

被引：130

作者：

Bültmann, BD

Klingel, K

Näbauer, M

Wallwiener, D

Kandolf, R

机构：

[1] Univ Tubingen Hosp, Inst Pathol, D-72076 Tubingen, Germany

[2] Univ Tubingen Hosp, Dept Gynecol & Obstet, D-72076 Tubingen, Germany

[3] Univ Munich, Dept Med 1, Munich, Germany

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2005年 / 193卷 / 02期

关键词：

peripartum cardiomyopathy; virus; molecular pathologic data; infiammatory cardiomyopathy;

D O I：

10.1016/j.ajog.2005.01.022

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Molecular pathologic investigation of endomyocardial biopsy specimens from 26 patients with peripartum cardiomyopathy revealed viral genomes (parvovirus B19, human herpes virus 6, Epstein-Barr virus, and human cytomegalovirus) in 8 patients (30.7%) that were associated immunohistologically with interstitial inflammation. These findings indicate a high prevalence of virus-associated inflammatory changes in peripartum cardiomyopathy. (c) 2005 Elsevier Inc. All rights reserved.

引用

页码：363 / 365

页数：3

共 8 条

[1]

Bültmann BD, 2004, NEW ENGL J MED, V350, P2006

[2] Fatal parvovirus B19-associated myocarditis clinically mimicking ischemic heart disease:: An endothelial cell-mediated disease [J].