See potassium run

被引:44
作者
Miller, C [1 ]
机构
[1] Brandeis Univ, Howard Hughes Med Inst, Dept Biochem, Waltham, MA 02468 USA
关键词
D O I
10.1038/35102126
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Nearly all cells have membranes spanned by potassium-conducting channel proteins, without which your nerves (and much else) simply wouldn't work. Ion permeation through these channels can now be seen in dazzling detail.
引用
收藏
页码:23 / 24
页数:2
相关论文
共 9 条
[1]   Energetics of ion conduction through the K+ channel [J].
Bernèche, S ;
Roux, B .
NATURE, 2001, 414 (6859) :73-77
[2]   The structure of the potassium channel:: Molecular basis of K+ conduction and selectivity [J].
Doyle, DA ;
Cabral, JM ;
Pfuetzner, RA ;
Kuo, AL ;
Gulbis, JM ;
Cohen, SL ;
Chait, BT ;
MacKinnon, R .
SCIENCE, 1998, 280 (5360) :69-77
[3]  
Hille B., 2001, Ion channels of excitable membranes, V3rd
[4]   THE POTASSIUM PERMEABILITY OF A GIANT NERVE FIBRE [J].
HODGKIN, AL ;
KEYNES, RD .
JOURNAL OF PHYSIOLOGY-LONDON, 1955, 128 (01) :61-88
[5]   The barium site in a potassium channel by X-ray crystallography [J].
Jiang, YX ;
MacKinnon, R .
JOURNAL OF GENERAL PHYSIOLOGY, 2000, 115 (03) :269-272
[6]   KcsA: It's a potassium channel [J].
LeMasurier, M ;
Heginbotham, L ;
Miller, C .
JOURNAL OF GENERAL PHYSIOLOGY, 2001, 118 (03) :303-313
[7]   Energetic optimization of ion conduction rate by the K+ selectivity filter [J].
Morais-Cabral, JH ;
Zhou, YF ;
MacKinnon, R .
NATURE, 2001, 414 (6859) :37-42
[8]   DISCRETE BA2+ BLOCK AS A PROBE OF ION OCCUPANCY AND PORE STRUCTURE IN THE HIGH-CONDUCTANCE CA2+-ACTIVATED K+ CHANNEL [J].
NEYTON, J ;
MILLER, C .
JOURNAL OF GENERAL PHYSIOLOGY, 1988, 92 (05) :569-586
[9]   Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 Å resolution [J].
Zhou, YF ;
Morais-Cabral, JH ;
Kaufman, A ;
MacKinnon, R .
NATURE, 2001, 414 (6859) :43-48