Scope and limitation of the [1,4] SPh shift in the synthesis of allylic alcohols

被引：17

作者：

Eames, J

delasHeras, MA

Jones, RVH

Warren, S

机构：

[1] UNIV CAMBRIDGE,CHEM LAB,CAMBRIDGE CB2 1EW,ENGLAND

[2] ZENECA GRANGEMOUTH WORKS,PROC TECHNOL DEPT,GRANGEMOUTH FK3 8XG,SCOTLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 07期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/0040-4039(95)02319-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Rearrangement of 4-PhS-1,3-diols with TsCl in pyridine gives allylic alcohols. We discuss the scope and limitaton of this reaction using structural variations, which help to elucidate the mechanism of the reaction. All reactions proceed in high yield and give synthetically useful products.

引用

页码：1117 / 1120

页数：4

共 6 条

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