Forced vital capacity, slow vital capacity, or inspiratory vital capacity: Which is the best measure of vital capacity?

被引:51
作者
Chhabra, SK [1 ]
机构
[1] Univ Delhi, Vallabhbhai Patel Chest Inst, Dept Cardioresp Physiol, Delhi 110007, India
关键词
bronchial asthma; pathophysiology; pulmonary function; spirometry;
D O I
10.3109/02770909809075669
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Vital capacity can be measured as forced vital capacity (FVC), slow vital capacity (SVC), and inspiratory vital capacity (IVC). Although it is well known that the latter two are generally greater, a systematic comparison of the three in subjects with different degrees of airways obstruction has not been made. Sixty asthmatics and 20 normal subjects performed maneuvers for measurement of FVC, SVC, and IVC on a dry, rolling-seal spirometer. The severity of airways obstruction in asthmatics was classified as mild, moderate, and severe. There was no significant difference between FVC, SVC, and IVC in normal subjects. However, the three measurements of vital capacity were significantly different in all subgroups of asthmatics. FVC was smaller than both SVC and IVC. The differences were more marked in patients with moderate and severe degrees of airways obstruction.The differences between SVC and IVC were small and clinically not important. Forced expiratory volume in 1 sec (FEV1) expressed as percent of FVC, SVC, and IVC, was not different in normals and asthmatics with mild airways obstruction. The ratios were significantly different in asthmatics with moderate and severe airways obstruction. FEV1/IVC ratio was the lowest in both the groups followed by FEV1/SVC and FEV1/FVC. IVC and SVC are greater than FVC in patients with airways obstruction. This difference increases as the degree of obstruction increases. The difference between SVC or IVC and FVC serves as an indicator of air trapping. Both FVC and IVC could be measured and the largest VC used to calculate the FEV1/VC ratio because this increases the sensitivity of spirometry in detecting airways obstruction.
引用
收藏
页码:361 / 365
页数:5
相关论文
共 7 条
[1]  
American Thoracic Society, 1987, AM REV RESPIR DIS, V136, P1286
[3]   ALVEOLAR SHAPE CHANGES WITH VOLUME IN ISOLATED, AIR-FILLED LOBES OF CAT LUNG [J].
KLINGELE, TG ;
STAUB, NC .
JOURNAL OF APPLIED PHYSIOLOGY, 1970, 28 (04) :411-&
[4]   MECHANISMS DETERMINING RESIDUAL VOLUME OF LUNGS IN NORMAL SUBJECTS [J].
LEITH, DE ;
MEAD, J .
JOURNAL OF APPLIED PHYSIOLOGY, 1967, 23 (02) :221-&
[5]   FACTORS LIMITING DEPTH OF A MAXIMAL INSPIRATION IN HUMAN SUBJECTS [J].
MEAD, J ;
TURNER, JM ;
MILICEMILL, J .
JOURNAL OF APPLIED PHYSIOLOGY, 1963, 18 (02) :295-&
[6]   LUNG-VOLUMES AND FORCED VENTILATORY FLOWS - REPORT WORKING PARTY STANDARDIZATION OF LUNG-FUNCTION TESTS EUROPEAN-COMMUNITY FOR STEEL AND COAL - OFFICIAL STATEMENT OF THE EUROPEAN RESPIRATORY SOCIETY [J].
QUANJER, PH ;
TAMMELING, GJ ;
COTES, JE ;
PEDERSEN, OF ;
PESLIN, R ;
YERNAULT, JC .
EUROPEAN RESPIRATORY JOURNAL, 1993, 6 :5-40
[7]  
SLAGTER B, 1955, ACTA PHYSIOL PHARM N, V4, P419