Microtubule dynamics: New surprises from an old MAP

被引:12
作者
McNally, F [1 ]
机构
[1] Univ Calif Davis, Sect Mol & Cellular Biol, Davis, CA 95616 USA
关键词
D O I
10.1016/S0960-9822(03)00524-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Dis1/XMAP215 family microtubule-binding proteins are essential for cell division in animals, plants and fungi, suggesting a conserved cell-division mechanism used by all eukaryotes. Two new studies, however, reveal that different family members can have very different effects on microtubule dynamics.
引用
收藏
页码:R597 / R599
页数:3
相关论文
共 21 条
[1]   Surfing on microtubule ends [J].
Carvalho, P ;
Tirnauer, JS ;
Pellman, D .
TRENDS IN CELL BIOLOGY, 2003, 13 (05) :229-237
[2]   mini spindles:: A gene encoding a conserved microtubule-associated protein required for the integrity of the mitotic spindle in Drosophila [J].
Cullen, CF ;
Deák, P ;
Glover, DM ;
Ohkura, H .
JOURNAL OF CELL BIOLOGY, 1999, 146 (05) :1005-1018
[3]   Spindle-kinetochore attachment requires the combined action of Kin I-like KIp5/6 and AIp14/Dis1-MAPs in fission yeast [J].
Garcia, MA ;
Koonrugsa, N ;
Toda, T .
EMBO JOURNAL, 2002, 21 (22) :6015-6024
[4]   A MICROTUBULE-ASSOCIATED PROTEIN FROM XENOPUS EGGS THAT SPECIFICALLY PROMOTES ASSEMBLY AT THE PLUS-END [J].
GARD, DL ;
KIRSCHNER, MW .
JOURNAL OF CELL BIOLOGY, 1987, 105 (05) :2203-2215
[5]   The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells [J].
Gergely, F ;
Draviam, VM ;
Raff, JW .
GENES & DEVELOPMENT, 2003, 17 (03) :336-341
[6]   Reconstitution of physiological microtubule dynamics using purified components [J].
Kinoshita, K ;
Arnal, I ;
Desai, A ;
Drechsel, DN ;
Hyman, AA .
SCIENCE, 2001, 294 (5545) :1340-1343
[7]   Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast [J].
Kosco, KA ;
Pearson, CG ;
Maddox, PS ;
Wang, PJJ ;
Adams, IR ;
Salmon, ED ;
Bloom, K ;
Huffaker, TC .
MOLECULAR BIOLOGY OF THE CELL, 2001, 12 (09) :2870-2880
[8]   Poleward microtubule flux is a major component of spindle dynamics and anaphase A in mitotic Drosophila embryos [J].
Maddox, P ;
Desai, A ;
Oegema, K ;
Mitchison, TJ ;
Salmon, ED .
CURRENT BIOLOGY, 2002, 12 (19) :1670-1674
[9]   ZYG-9, a Caenorhabditis elegans protein required for microtubule organization and function, is a component of meiotic and mitotic spindle poles [J].
Matthews, LR ;
Carter, P ;
Thierry-Mieg, D ;
Kemphues, K .
JOURNAL OF CELL BIOLOGY, 1998, 141 (05) :1159-1168
[10]   POLEWARD KINETOCHORE FIBER MOVEMENT OCCURS DURING BOTH METAPHASE AND ANAPHASE-A IN NEWT LUNG-CELL MITOSIS [J].
MITCHISON, TJ ;
SALMON, ED .
JOURNAL OF CELL BIOLOGY, 1992, 119 (03) :569-582