Inhibitory neuropeptide receptors on macrophages

被引：29

作者：

Ganea, D

Delgado, L

机构：

[1] Rutgers State Univ, Dept Biol Sci, Newark, NJ 07102 USA

[2] Univ Complutense, Fac Biol, Dept Biol Celular, E-28040 Madrid, Spain

来源：

MICROBES AND INFECTION | 2001年 / 3卷 / 02期

关键词：

neuropeptides; macrophages; receptors;

D O I：

10.1016/S1286-4579(00)01361-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The immune response, both in innate and adaptive immunity, is controlled at several levels, including signaling from the central nervous system. Neuropeptides released within the lymphoid organs modulate the immune response, either as stimulators or inhibitors. The subject of this review is the description of macrophage-expressed receptors of inhibitory neuropeptides. We describe the inhibitory effects on macrophage function for several neuropeptides, the receptors that mediate those activities, and the molecular mechanisms initiated by some of these receptors in terms of transduction pathways and transcriptional factors. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

收藏

页码：141 / 147

页数：7

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