A transcriptional pause synchronizes translation with transcription in the tryptophanase operon leader region

被引：27

作者：

Gong, F ^{[1
]}

Yanofsky, C ^{[1
]}

机构：

[1] Stanford Univ, Dept Biol Sci, Stanford, CA 94305 USA

来源：

JOURNAL OF BACTERIOLOGY | 2003年 / 185卷 / 21期

关键词：

D O I：

10.1128/JB.185.21.6472-6476.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Regulation of transcription of the tryptophanase operon requires that translation of its leader peptide coding region, tnaC, be coupled with its transcription. We show in vitro that a transcription pause site exists at the end of the tnaC coding region and that translation of tnaC releases the paused transcription complex, coupling transcription with translation.

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页码：6472 / 6476

页数：5

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