New cyclopropyl-triterpenoids from the aerial roots of Ficus microcarpa

被引：27

作者：

Chiang, YM ^{[1
]}

Su, JK ^{[1
]}

Liu, YH ^{[1
]}

Kuo, YH ^{[1
]}

机构：

[1] Natl Taiwan Univ, Dept Chem, Taipei 10764, Taiwan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2001年 / 49卷 / 05期

关键词：

Ficus microcarpa; Moraceae; aerial roots; triterpene; 27-nor-3; beta-hydroxy-25-oxocycloartane; (22E)-25,26,27-trinor-3 beta-hydroxycycloart-22-en-24-al;

D O I：

10.1248/cpb.49.581

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Four new cyclopropyl-triterpenes, 27-nor-3 beta -hydroxy-25-oxoc3cloartane (1), (22E)-25,26,27-trinor-3 beta -hydroxycycloart-22-en-24-al (2), 3 beta acetoxy-15 alpha -hydroxy-13,27-cyclours-11-ene (3), 3 beta -acetoxy-12 alpha -formyloxy-13,27-cycloursan-11 alpha -ol (4), together with (23E)-27-nor-3 beta -hydroxycycloart-23-en-25-one (5) were isolated from the aerial roots of Ficus microcarpa. Compounds 3 and 4 are rare 13,27-cycloursane-type triterpenes. Their structures were elucidated by spectroscopic and chemical methods.

引用

页码：581 / 583

页数：3

共 13 条

[1] PHYLLANTHOL - A NEW ALCOHOL FROM THE ROOT BARK OF PHYLLANTHUS-ENGLERI (PAX) [J].

ALBERMAN, KB ;

KIPPING, FB .

JOURNAL OF THE CHEMICAL SOCIETY, 1951, (SEP) :2296-2297

[2] Short side-chain cycloartanes from Tillandsia usneoides [J].

Cabrera, GM ;

Seldes, AM .

PHYTOCHEMISTRY, 1997, 45 (05) :1019-1021

[3] Taraxastane-type triterpenes from the aerial roots of Ficus microcarpa [J].

Chiang, YM ;

Kuo, YH .

JOURNAL OF NATURAL PRODUCTS, 2000, 63 (07) :898-901

[4]

HIGA M, 1987, B COLL SCI U RYUKYUS, V13, P75

[5]

Ibers J.A., 1974, INT TABLES XRAY CRYS, VIV

[6]

Kuo YH, 1999, CHEM PHARM BULL, V47, P498, DOI 10.1248/cpb.47.498

[7]

Kuo YH, 1999, CHEM PHARM BULL, V47, P299, DOI 10.1248/cpb.47.299

[8] Constituents of the bark of Ficus microcarpa Lf [J].

Kuo, YH ;

Li, YC .

JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1997, 44 (03) :321-325

[9]

Kuo YH, 2000, CHEM PHARM BULL, V48, P593

[10] Two new isoflavones from the bark of Ficus microcarpa [J].

Li, YC ;

Kuo, YH .

JOURNAL OF NATURAL PRODUCTS, 1997, 60 (03) :292-293

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