First efficient palladium-catalyzed Heck reactions of aryl bromides with alkyl methacrylate

被引：96

作者：

Beller, M

Riermeier, TH

机构：

[1] Anorganisch-chemisches Institut, 85747 Garching, TU München

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 36期

关键词：

D O I：

10.1016/0040-4039(96)01442-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient palladium-catalyzed coupling reaction of aryl bromides with butyl methacrylate has been developed. Depending on the reaction conditions various amounts of butyl 3-aryl-2-methylpropenoate and butyl 3-aryl-2-methyliden-propenoate as well as double arylated products were produced. Superior turn over numbers up to 8300 and turn over frequencies up to 1000 h(-1) for Heck reactions of aryl bromides with methacrylic acid ester have been obtained for the first rime. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：6535 / 6538

页数：4

共 16 条

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