Genetic algorithms for modelling and optimisation

被引：666

作者：

McCall, J ^{[1
]}

机构：

[1] Robert Gordon Univ, Sch Comp, Aberdeen AB9 1FR, Scotland

来源：

JOURNAL OF COMPUTATIONAL AND APPLIED MATHEMATICS | 2005年 / 184卷 / 01期

关键词：

genetic algorithms; immunology; optimisation; evolution;

D O I：

10.1016/j.cam.2004.07.034

中图分类号：

O29 [应用数学];

学科分类号：

070104 ;

摘要：

Genetic algorithms (GAs) are a heuristic search and optimisation technique inspired by natural evolution. They have been successfully applied to a wide range of real-world problems of significant complexity. This paper is intended as an introduction to GAs aimed at immunologists and mathematicians interested in immunology. We describe how to construct a GA and the main strands of GA theory before speculatively identifying possible applications of GAs to the study of immunology. An illustrative example of using a GA for a medical optimal control problem is provided. The paper also includes a brief account of the related area of artificial immune systems. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：205 / 222

页数：18

共 37 条

[1]

[Anonymous], PRACTICE AUTONOMOUS

[2]

[Anonymous], 1988, Mathematical models in cancer research

[3]

[Anonymous], 1991, Handbook of genetic algorithms

[4]

Back T., 1997, Handbook of evolutionary computation

[5]

BACK T, 1991, P 4 INT C GEN ALG LO

[6] Modelling the dynamics of LCMV infection in mice: II. Compartmental structure and immunopathology [J].

Bocharov, G ;

Klenerman, P ;

Ehl, S .

JOURNAL OF THEORETICAL BIOLOGY, 2003, 221 (03) :349-378

[7] Exploring novel chemotherapy treatments using the WWW [J].

Boyle, J ;

Henderson, D ;

McCall, J ;

McLeod, H ;

Usher, J .

INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS, 1997, 47 (1-2) :107-114

[8]

BROWN DF, 2000, P IASTED INT C ART I

[9]

Cassidy J., 1995, Pharmaceutical Medicine (London), V9, P95

[10] In silico models for cellular and molecular immunology:: successes, promises and challenges [J].

Chakraborty, AK ;

Dustin, ML ;

Shaw, AS .

NATURE IMMUNOLOGY, 2003, 4 (10) :933-936

← 1 2 3 4 →