2,2,6,6-tetramethyl-1-piperidinyl-oxyl/[bis(acetoxy)-iodo]benzene-mediated oxidation: A versatile and convenient route to poly(ethylene glycol) aldehyde or carboxylic acid derivatives

被引：22

作者：

Masson, C ^{[1
]}

Scherman, D ^{[1
]}

Bessodes, M ^{[1
]}

机构：

[1] Ecole Natl Super Chimi Paris, Aventis Pharma Gencell, UMR7001 CNRS, Lab Chim Bioorgan & Biotechnol Mol & Cellulaire, F-94403 Vitry Sur Seine, France

来源：

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY | 2001年 / 39卷 / 22期

关键词：

functionalization of polymers; catalysis; selectivity; carboxylic acid; aldehyde;

D O I：

10.1002/pola.10049

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A new and very convenient route to oxidized poly(ethylene glycol), with a catalytic nitroxyl radical oxidant (2,2,6,6-tetramethyl-1-piperidinyl-oxyl) regenerated in situ by stoichiometric amounts of [bis(acetoxy)-iodo]benzene, is described. Under these conditions, the reaction is quantitative and leads to the pure product by a simple process such as precipitation and washing with diethyl ether. (C) 2001 John Wiley & Sons, Inc.

引用

页码：4022 / 4024

页数：3

共 23 条

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