Enhanced catalytic DNAzyme for label-free colorimetric detection of DNA

被引：92

作者：

Li, Tao

Dong, Shaojun

Wang, Erkang ^{[1
]}

机构：

[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China

[2] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 41期

关键词：

D O I：

10.1039/b712165b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A DNAzyme-based label-free method for the colorimetric detection of DNA is introduced, with a supramolecular hemin G-quartet complex as the sensing element and a 36-mer single-strand DNA as the analyte that is detected at 10 nM.

引用

页码：4209 / 4211

页数：3

共 26 条

[1]

Breaker R R, 1994, Chem Biol, V1, P223, DOI 10.1016/1074-5521(94)90014-0

[2] DNA enzymes [J].

Breaker, RR .

NATURE BIOTECHNOLOGY, 1997, 15 (05) :427-431

[3] A DNA ENZYME WITH MG2+-DEPENDENT RNA PHOSPHOESTERASE ACTIVITY [J].

BREAKER, RR ;

JOYCE, GF .

CHEMISTRY & BIOLOGY, 1995, 2 (10) :655-660

[4] Cofactor-assisted self-cleavage in DNA libraries with a 3'-5'-phosphoramidate bond [J].

Burmeister, J ;

vonKiedrowski, G ;

Ellington, AD .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1997, 36 (12) :1321-1324

[5] Cleaving DNA with DNA [J].

Carmi, N ;

Balkhi, SR ;

Breaker, RR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (05) :2233-2237

[6] In vitro selection of self-cleaving DNAs [J].

Carmi, N ;

Shultz, LA ;

Breaker, RR .

CHEMISTRY & BIOLOGY, 1996, 3 (12) :1039-1046

[7] Diagnosing viruses by the rolling circle amplified synthesis of DNAzymes [J].

Cheglakov, Zoya ;

Weizmann, Yossi ;

Basnar, Bernhard ;

Willner, Itamar .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2007, 5 (02) :223-225

[8] STEADY-STATE KINETICS OF PEROXIDASE WITH 2,2'-AZINO-DI-(3-ETHYLBENZTHIAZOLINE-6-SULPHONIC ACID) AS CHROMOGEN [J].

CHILDS, RE ;

BARDSLEY, WG .

BIOCHEMICAL JOURNAL, 1975, 145 (01) :93-103

[9] A DNA METALLOENZYME WITH DNA-LIGASE ACTIVITY [J].

CUENOUD, B ;

SZOSTAK, JW .

NATURE, 1995, 375 (6532) :611-614

[10] Deoxyribozymes: new activities and new applications [J].

Emilsson, GM ;

Breaker, RR .

CELLULAR AND MOLECULAR LIFE SCIENCES, 2002, 59 (04) :596-607

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