An efficient and practical procedure for the synthesis of 4-substituted coumarins

被引：76

作者：

De, SK ^{[1
]}

Gibbs, RA ^{[1
]}

机构：

[1] Purdue Univ, Purdue Canc Ctr, Sch Pharm, Dept Med Chem & Mol Pharmacol, W Lafayette, IN 47907 USA

来源：

SYNTHESIS-STUTTGART | 2005年 / 08期

关键词：

phenols; beta-keto ester; Pechmann reaction; bismuth(III) chloride; coumarin;

D O I：

10.1055/s-2005-865282

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

BiCl3 is used as an efficient catalyst in the Pechmann condensation reaction of phenols with beta-keto esters leading to the formation of coumarin derivatives in excellent yields under solvent-free conditions.

引用

页码：1231 / 1233

页数：3

共 22 条

[1]

[Anonymous], J CHEM SOC

[2]

BISWAS GK, 1992, INDIAN J CHEM B, V31, P628

[3] Bismuth trichloride catalyzed synthesis of α-aminonitriles [J].

De, SK ;

Gibbs, RA .

TETRAHEDRON LETTERS, 2004, 45 (40) :7407-+

[4] Scandium chloride-catalyzed chemoselective thioacetalization of aldehydes [J].

De, SK .

SYNTHESIS-STUTTGART, 2004, (06) :828-830

[5] Ruthenium(III) chloride catalyzed acylation of alcohols, phenols, thiols, and amines [J].

De, SK .

TETRAHEDRON LETTERS, 2004, 45 (14) :2919-2922

[6] Ruthenium(III) chloride-catalyzed chemoselective synthesis of acetals from aldehydes [J].

De, SYK ;

Gibbs, RA .

TETRAHEDRON LETTERS, 2004, 45 (44) :8141-8144

[7]

Gunnewegh EA, 1996, RECL TRAV CHIM PAY B, V115, P226

[8]

HOZ ADL, 1999, SYNLETT, P608

[9]

Johnson J.R., 1942, Organic Reactions, Org. React., V1, P210, DOI DOI 10.1002/0471264180.OR001.08

[10]

Jones G., 1967, ORGANICREACTIONS, V15, P204, DOI [DOI 10.1002/0471264180.OR015.02, 10.1002/0471264180.or015.02]

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