HIV-inhibitory natural products.: 50.: Vismiaphenones D-G, new prenylated benzophenones from Vismia cayennensis

被引：55

作者：

Fuller, RW ^{[1
]}

Westergaard, CK ^{[1
]}

Collins, JW ^{[1
]}

Cardellina, JH ^{[1
]}

Boyd, MR ^{[1
]}

机构：

[1] NCI, Frederick Canc Res & Dev Ctr, Div Canc Treatment & Diag, Lab Drug Discovery Res & Dev,Dev Therapeut Progra, Frederick, MD 21702 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 01期

关键词：

D O I：

10.1021/np980152w

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Following anti-HIV bioassay-guided fractionation, four new prenylated benzophenones, vismiaphenones D-G (7-10), were isolated from extracts of leaves of Vismia cayennensis. The structures were elucidated by spectral analyses. Only vismiaphenone D (7) exhibited HIV-inhibitory activity in the NCI primary screen.

引用

页码：67 / 69

页数：3

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