Malaria:: Historical aspects and chemoterapy

被引：38

作者：

Franca, Tanos C. C. ^{[1
]}

dos Santos, Marta G. ^{[1
]}

Figueroa-Villar, Jose D. ^{[1
]}

机构：

[1] Inst Mil Engn, Div Ensino & Pesquisa, Secao Engn Quim, BR-22290270 Rio De Janeiro, Brazil

来源：

QUIMICA NOVA | 2008年 / 31卷 / 05期

关键词：

malaria; historical of malaria; antimalaric chemotherapy;

D O I：

10.1590/S0100-40422008000500060

中图分类号：

O6 [化学];

学科分类号：

0703 [化学];

摘要：

Malaria is still a very serious worldwide public health problem affecting between 300 and 500 million people and causing from 1.0 to 2.5 million deaths annually. The major problems with this disease are the lack of efficient vaccines and the rapid emergence of chemotherapy resistant P. falciparum strains. In this work we present a synopsis and discussion on malaria to provide the renders with some information on the historical aspects and relevance of this disease as well as the chemotherapy in use today.

引用

页码：1271 / 1278

页数：8

共 51 条

[1]

ACKERKNECHT EH, 1966, MALARIA UPPER MISSIS

[2]

[Anonymous], 1997, WHO REPORT

[3]

Bruce-Chwatt L. J., 1988, Malaria: principles and practice of malariology. Volume 1., P1

[4]

Celli A, 1925, STORIA MALARIA NELLA

[5]

Invasion of red blood cells by malaria parasites [J].

Cowman, AF ;

Crabb, BS .

CELL, 2006, 124 (04) :755-766

[6]

Molecular modeling of wild-type and antifolate resistant mutant Plasmodium falciparum DHFR [J].

Delfino, RT ;

Santos, OA ;

Figueroa-Villar, JD .

BIOPHYSICAL CHEMISTRY, 2002, 98 (03) :287-300

[7]

Delfino RT, 2002, J BRAZIL CHEM SOC, V13, P727, DOI 10.1590/S0103-50532002000600003

[8]

Duffy John., 1953, Epidemics in Colonial America

[9]

FILHO OAS, 2001, BIOPHYS CHEM, V91, P305

[10]

FILHO OAS, 2000, THESIS I MILITAR ENG

← 1 2 3 4 5 6 →