BAliBASE (Benchmark Alignment dataBASE): enhancements for repeats, transmembrane sequences and circular permutations

被引：130

作者：

Bahr, A ^{[1
]}

Thompson, JD ^{[1
]}

Thierry, JC ^{[1
]}

Poch, O ^{[1
]}

机构：

[1] Inst Genet & Biol Mol & Cellulaire, Lab Biol & Genom Struct, CNRS, INSERM,ULP, F-67404 Illkirch Graffenstaden, France

来源：

NUCLEIC ACIDS RESEARCH | 2001年 / 29卷 / 01期

关键词：

D O I：

10.1093/nar/29.1.323

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

BAliBASE is specifically designed to serve as an evaluation resource to address all the problems encountered when aligning complete sequences, The database contains high quality, manually constructed multiple sequence alignments together with detailed annotations. The alignments are all based on three-dimensional structural superpositions, with the exception of the transmembrane sequences. The first release provided sets of reference alignments dealing with the problems of high variability, unequal repartition and large NIC-terminal extensions and internal insertions. Here we describe version 2.0 of the database, which incorporates three new reference sets of alignments containing structural repeats, transmembrane sequences and circular permutations to evaluate the accuracy of detection/prediction and alignment of these complex sequences. BAliBASE can be viewed at the web site http://www-igbmc.u-strasbg.fr/ BioInfo/BAliBASE2/index.html or can be downloaded from ftp://ftp-igbmc.u-strasbg.fr/pub/BAIiBASE2/.

引用

页码：323 / 326

页数：4

共 19 条

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