The DAPIN family: a novel domain links apoptotic and interferon response proteins

被引：87

作者：

Staub, E ^{[1
]}

Dahl, E ^{[1
]}

Rosenthal, A ^{[1
]}

机构：

[1] metaGen Gesellsch Genomforsch mbh, D-14195 Berlin, Germany

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2001年 / 26卷 / 02期

关键词：

D O I：

10.1016/S0968-0004(00)01717-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We report the discovery of a protein domain, hereafter referred to as DAPIN, in diverse vertebrate and viral proteins that is associated with tumor biology apoptosis and inflammation. Based on a secondary structure prediction, we suggest an all-alpha fold for DAPIN, which is also adopted by apoptotic protein domains of the CARD, death domain and death effector domain type.

引用

页码：83 / 85

页数：3

共 26 条

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