Protective role of L-carnitine on liver and heart lipid peroxidation in atherosclerotic rats

被引:53
作者
Dayanandan, A [1 ]
Kumar, P [1 ]
Panneerselvam, C [1 ]
机构
[1] Univ Madras, Post Grad Inst Basic Med Sci, Dept Biochem, Chennai 113, India
关键词
lipid peroxides; hyperlipidemia; carnitine; vitamins; antioxidants;
D O I
10.1016/S0955-2863(00)00151-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Lipid peroxides are considered to be the initiation factor for atherosclerosis. Present study depicts that L-carnitine treatment (300 mg/kg body weight/day) for 7 and 14 days caused significant reduction in the tissue lipid peroxidations. It also shows marked improvement in the antioxidant status. By this way carnitine maintain the normal function of the cells. (C) 2001 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:254 / 257
页数:4
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